Related Experiment Videos
CD5 expression in human B-cell populations
P Youinou1, C Jamin, P M Lydyard
1Laboratory of Immunology, Institut de Synergie des Sciences et de la Santé, Brest University Medical School Hospital, BP 824, F-29609 Brest Cedex, France. youinou@univ-brest.fr
Immunology Today
|June 24, 1999
Abstract:
The origin of CD5+ B cells remains controversial. The differential response to ligation of CD5 resulting in apoptosis or proliferation provides insight into its roles in distinct human B cells. Here, Pierre Youinou, Christophe Jamin and Peter Lydyard review current knowledge of B-1 and B-2 cells, and propose that CD5 has different functions when expressed by different B-cell subpopulations.