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Aneurysmal bone cyst. A population based epidemiologic study and literature review
A Leithner1, R Windhager, S Lang
1Department of Orthopedic Surgery, Vienna University Hospital, Austria.
Clinical Orthopaedics and Related Research
|June 24, 1999
Summary
Aneurysmal bone cysts (ABCs) are rare bone lesions. This study found an annual incidence of 0.14 per 10(5) individuals, with a slight predilection for females.
Area of Science:
- Orthopedics
- Oncology
- Epidemiology
Background:
- Aneurysmal bone cyst (ABC) is a rare, non-neoplastic, expansile osteolytic bone lesion.
- The etiology of ABCs remains unknown.
- No previous epidemiologic studies on ABC incidence have been reported.
Purpose of the Study:
- To determine the incidence of primary aneurysmal bone cysts.
- To analyze gender and age predilection in patients with ABCs.
Main Methods:
- Retrospective, population-based analysis of 94 patients with primary ABC.
- Literature review of 1002 patients with ABCs.
Main Results:
- The annual incidence of primary ABC was 0.14 per 10(5) individuals.
- The male to female ratio was 1:1.04.
- The median age of affected individuals was 13 years (range, 1-59 years).
Conclusions:
- ABCs occur more frequently in female patients.
- This study provides crucial epidemiologic data for aneurysmal bone cysts.