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Description of a possible clonal expansion of Plasmodium vivax in Manaus-Amazonas-Brazil
M dos G Alecrim1, W D Alecrim, V Macêdo
1Fundação de Medicina Tropical do Amazonas da Universidade do Amazonas, Brasília.
Revista Da Sociedade Brasileira De Medicina Tropical
|June 25, 1999
Abstract:
Atypical P. vivax cases reported in Manaus municipality led us to detect a genetic isolate of P. vivax. Variable regions of SSUrRNA were examined from the initial time of infection and in the two recrudescences/relapses from a patient exhibiting chloroquine and primaquine resistance. A unique isolate, found at all stages of infection, suggests the presence of a clonal expansion.