Postpartum period: a risk factor for neuroleptic malignant syndrome

Neuroleptic malignant syndrome (NMS) occurred in four postpartum patients treated with various psychotropic medications including depot-neuroleptics over a 5-year period. All four patients had the onset of NMS in the first few weeks of the postpartum period. Whether or not there is an increased risk for the development of NMS in the puerperium period is discussed.