Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Type III intermittency in human partial epilepsy.

J L Velazquez1, H Khosravani, A Lozano

  • 1Playfair Neuroscience Unit, Bloorview Epilepsy Programme, University of Toronto, Ontario M5T 2S8, Canada. jlpv@playfair.utoronto.ca

The European Journal of Neuroscience
|June 26, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lysergic acid diethylamide modulates hippocampal and cortical local field potential oscillatory rhythms in male mice.

Brain research·2026
Same author

<i>Bacteroidetes</i> promote hepatocellular carcinoma progression and resistance to immunotherapy.

bioRxiv : the preprint server for biology·2025
Same author

Cross-sectional and longitudinal Biomarker extraction and analysis for multicentre FLAIR brain MRI.

Neuroimage. Reports·2025
Same author

Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography.

Nature medicine·2025
Same author

Dentine surface morphology according to caries removal method and subsequent acid etching.

European journal of paediatric dentistry·2024
Same author

Neutrino-Induced Coherent π^{+} Production in C, CH, Fe, and Pb at ⟨E_{ν}⟩∼6  GeV.

Physical review letters·2023
Same journal

Hyperthyroidism Is Genetically Associated With Reduced Risk of Parkinson's Disease: A Mendelian Randomization Analysis.

The European journal of neuroscience·2026
Same journal

How Precise Is Predictive Coding for Things We Hear? Mismatch Negativity With Shepard Tones.

The European journal of neuroscience·2026
Same journal

Can Neuroscience Inform Peacebuilding?

The European journal of neuroscience·2026
Same journal

Game-Based Foreign-Language Speech Rehearsal Improves Pitch Processing Beyond Speech Domain.

The European journal of neuroscience·2026
Same journal

Sleep Oscillations Across Cortical, Subcortical and Cerebellar Structures in Magnetoencephalography.

The European journal of neuroscience·2026
Same journal

Freezing of Gait Levodopa Response Pattern in Parkinson's Disease Provides Clues to Pathophysiology.

The European journal of neuroscience·2026
See all related articles

Understanding human seizures requires characterizing their dynamics. This study reveals that type III intermittency, a dynamic regime, characterizes seizure events, explaining abrupt transitions.

Area of Science:

  • Neuroscience
  • Epilepsy research
  • Nonlinear dynamics

Background:

  • Human seizures represent complex dynamic events.
  • Understanding seizure transitions is crucial for developing control strategies.
  • Previous characterizations of seizure dynamics lack rigor.

Purpose of the Study:

  • To rigorously characterize the dynamic regimes underlying human partial epilepsy seizures.
  • To elucidate the dynamics governing the transition to and progression of seizures.
  • To identify the specific dynamic regime characteristic of ictal events.

Main Methods:

  • Recorded intra- or extracranial brain electrical activity in five epilepsy patients.
  • Analyzed interictal and ictal activity to determine seizure dynamics.

Related Experiment Videos

  • Constructed first-return one-dimensional maps from interpeak intervals.
  • Utilized histograms of regular phase durations during seizures for confirmation.

    • Main Results:

    • Analysis revealed type III intermittency as the dynamic characteristic of ictal events.
    • First-return maps exhibited features consistent with type III intermittency.
    • Histograms confirmed the presence of regular phases during seizures, supporting the intermittent regime model.
    • The intermittent regime model explains abrupt seizure transitions via transient stabilization.

    Conclusions:

    • Human partial epilepsy seizures exhibit type III intermittency.
    • This dynamic regime provides a framework for understanding abrupt seizure transitions.
    • Characterizing seizure dynamics offers potential pathways for seizure control.