Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Familial hypertrophic cardiomyopathy.

¹Department of Medical-Surgical Nursing, University of Illinois, Chicago, USA.

The Journal of Cardiovascular Nursing

|July 1, 1999

Summary

Familial hypertrophic cardiomyopathy (FHC) is a genetic heart condition affecting 0.2% of people. Research explores genetic mutations and risk factors linked to severe hypertrophy and sudden cardiac death in FHC patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cannabis Smoking and Cardiovascular Health: It's Complicated.

Clinical pharmacology and therapeutics·2017

Same author

The effects of a liquid ethanol diet on nutritional status and fluid balance in the rat.

Alcohol and alcoholism (Oxford, Oxfordshire)·2001

Same author

A rodent model of alcoholic heart muscle disease and its evaluation by echocardiography.

Alcoholism, clinical and experimental research·2001

Same author

The natriuretic peptides: physiology and role in left-ventricular dysfunction.

Biological research for nursing·2001

Same author

AHA Science Advisory. Wine and your heart: A science advisory for healthcare professionals from the Nutrition Committee, Council on Epidemiology and Prevention, and Council on Cardiovascular Nursing of the American Heart Association.

Stroke·2001

Same author

AHA Science Advisory: Wine and your heart: a science advisory for healthcare professionals from the Nutrition Committee, Council on Epidemiology and Prevention, and Council on Cardiovascular Nursing of the American Heart Association.

Circulation·2001

Area of Science:

Cardiology
Genetics
Molecular Biology

Background:

Familial hypertrophic cardiomyopathy (FHC) affects 0.2% of the population.
Characterized by ventricular hypertrophy, primarily the intraventricular septum.
Caused by genetic mutations in sarcomeric proteins.

Purpose of the Study:

Provide new insights into genetic mutations causing FHC.
Discuss risk factors for severe hypertrophy and sudden death in FHC.

Main Methods:

Review of genetic mutations in sarcomeric proteins.
Analysis of clinical presentations and risk factors.

Main Results:

FHC exhibits genetic heterogeneity.
Diverse clinical presentations range from altered cardiac structure to sudden death.
Specific genetic mutations and risk factors are associated with severe outcomes.

Conclusions:

Understanding genetic mutations is key to FHC management.
Identifying risk factors can mitigate severe hypertrophy and sudden death.
Further research into FHC genetics and risk stratification is warranted.

Related Experiment Videos