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Related Experiment Videos

Risk factors for cancer cervix: a case control study.

V V Gawande1, S N Wahab, S P Zodpey

  • 1Dept. of Preventive and Social Medicine, Govt. Medical College and Hospital, Nagpur, Maharashtra, India.

Indian Journal of Cancer
|July 1, 1999
PubMed
Summary

Illiteracy, poor hygiene, long marriage, multiple births, and early menstruation are key risk factors for cervical cancer. Addressing these can significantly reduce the incidence of this major women's health issue.

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Area of Science:

  • Gynecology
  • Oncology
  • Public Health

Background:

  • Cervical cancer remains a significant global health challenge, particularly in certain populations.
  • Identifying modifiable risk factors is crucial for developing effective prevention strategies.

Purpose of the Study:

  • To investigate the independent and interactive roles of various risk factors in the development of cervical cancer.
  • To determine the etiological and preventable contributions of identified risk factors.

Main Methods:

  • A hospital-based, group-matched case-control study involving 230 cervical cancer cases and 230 controls.
  • Univariate analysis of 17 hypothesized risk factors, followed by multiple logistic regression (MLR) analysis.
  • Estimation of Attributable Risk Proportions (ARP) and Population Attributable Risk Proportion (PARP).

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Main Results:

  • Univariate analysis identified 10 significant risk factors.
  • MLR confirmed illiteracy, poor genital hygiene, long duration of married life, multiparity, and early menarche as significant predictors.
  • ARP and PARP estimates supported the etiological and preventable nature of these factors.

Conclusions:

  • Specific socio-demographic and behavioral factors significantly contribute to cervical cancer risk.
  • Targeting modifiable risk factors like hygiene and reproductive behaviors offers a viable public health strategy for cervical cancer prevention.
  • Developing targeted preventive strategies based on these findings is essential to reduce the burden of cervical cancer.