Related Experiment Video
Updated: Aug 9, 2026

07:59
Murine Full-thickness Skin Transplantation
Published on: January 2, 2017
Expectations and outcomes in organ transplantation
L P McChesney1, S S Braithwaite
1Section of Transplant Surgery, Rush Medical College, Chicago, IL, USA.
Summary
Understanding bad outcomes in transplantation is crucial. This research highlights the need for policy reform and improved humanistic care, including advance directives and hospice options, for transplant recipients experiencing adverse events.
Area of Science:
- Transplantation research
- Medical ethics
- Patient care outcomes
Background:
- The frequency and impact of adverse outcomes in organ transplantation require further investigation.
- Existing allocation policies and potential conflicts of interest may influence the occurrence of negative transplant results.
Purpose of the Study:
- To address the need for research into the frequency of adverse outcomes following organ transplantation.
- To emphasize the necessity for reforms in transplantation policies and practices.
- To outline strategies for providing humanistic care to transplant recipients experiencing poor outcomes.
Main Methods:
- Review of existing literature on transplantation outcomes.
- Analysis of factors influencing adverse events in transplant recipients.
- Development of recommendations for patient care and policy adjustments.
Main Results:
- Transplant recipients with poor outcomes often receive aggressive, potentially burdensome, medical interventions.
- Humanistic care for these patients necessitates attention to advance directives, shared decision-making regarding treatment alternatives, and hospice care options.
- Despite the occurrence of adverse events, the overall success rate and benefits of transplantation for good outcomes remain significant.
Conclusions:
- Reforms are needed to address the frequency and management of adverse outcomes in transplantation.
- Enhanced humanistic care, including palliative and hospice options, is essential for patients with poor transplant outcomes.
- The commitment to achieving positive transplantation results should be maintained, recognizing the profound benefits of successful organ replacement.
Keywords:
Health Care and Public HealthRelated Concept Videos
Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

