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A neural interface for a cortical vision prosthesis.

R A Normann1, E M Maynard, P J Rousche

  • 1Department of Bioengineering, University of Utah, Salt Lake City 84112, USA. narmann@m.cc.utah.edu

Vision Research
|July 9, 1999
PubMed
Summary
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Researchers developed a safe method to stimulate cortical neurons for vision prosthesis research. The Utah electrode array successfully evoked sensory perceptions, paving the way for artificial vision studies.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Ophthalmology

Background:

  • Cortically based vision prostheses require basic phosphene psychophysics research.
  • Stimulating cortical neurons for this research has been limited by a lack of safe, large-scale methods.

Purpose of the Study:

  • To evaluate the safety and efficacy of the Utah electrode array for stimulating cortical neurons.
  • To assess the potential of microelectrode arrays for phosphene psychophysics studies.

Main Methods:

  • Described the Utah electrode array design.
  • Conducted neurosurgical, physiological, and histological experiments to assess safety.
  • Performed chronic behavioral experiments to evaluate evoked sensory percepts.

Main Results:

Related Experiment Videos

  • Neurosurgical, physiological, and histological data suggest safe implantation in the visual cortex.
  • Electrical stimulation via the array evoked sensory percepts in behavioral experiments.

Conclusions:

  • The Utah electrode array shows promise for safe cortical stimulation.
  • High-count microelectrode arrays could facilitate phosphene psychophysics studies in humans.
  • This research offers a proof-of-concept for cortically based artificial vision.