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[A paraneoplastic acrosyndrome]
I Delèvaux1, J Cabane, E Le Nechet
1Service de Médecine interne, Hôpital Saint-Antoine, Paris.
Background:
Paraneoplastic digital ischemia is an uncommon complication of metastatic adenocarcinomas.
Case Report:
Two years after remission of an uterine adenocarcinoma, the patient developed an acrosyndrome involving all four limbs with digital ischemia. Recurrent carcinoma was evidenced by a very high antinuclear antibody titer. Chemotherapy improved the acrosyndrome.
Discussion:
Vasomotor disorders which developed in older subjects with no other signs of autoimmune disorders should suggest a neoplastic origin. Icshemia of the fingers would be caused by vasculitis. An elevated antinuclear antibody titer may be a supplementary argument suggesting a neoplastic etiology.