Related Experiment Video
Updated: Aug 15, 2026

A high-throughput method to globally study the organelle morphology in S. cerevisiae
Published on: March 2, 2009
Functional analysis of 12 ORFs from Saccharomyces cerevisiae chromosome II
S Rodríguez-Navarro1, F Estruch, J E Pérez-Ortín
1Departament de Bioquímica i Biología Molecular, Facultat de Ciències Biològiques, Universitat de València, Spain. jose.e.perez@uv.es
Abstract:
Twelve different ORFs have been deleted from the right arm of Saccharomyces cerevisiae chromosome II; namely YBR193c, YBR194w, YBR197c, YBR198c, YBR201w, YBR203w, YBR207w, YBR209w, YBR210w, YBR211c, YBR217w and YBR228w. Tetrad analysis of heterozygous deletant strains revealed that YBR193c, YBR198c and YBR211c are essential genes for vegetative growth. No effects were detected in any of the haploid deletion mutants for the rest of the ORFs with respect to growth, gross morphology or mating.
Related Concept Videos
Protein Complexes with Interchangeable Parts
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order to...
Chromosome Structure
The centromere is a DNA sequence that links sister chromatids. This is also where kinetochores, protein complexes to which spindle microtubules attach, are constructed after the chromosome is replicated. The kinetochores allow the spindle microtubules to move the chromosomes within the cell during cell division.
Telomeres consist of non-coding repetitive nucleotide...
Prokaryotic Gene Structure and Organization

