Prostate-specific antigen (PSA) in human seminal plasma

Prostate-specific antigen (PSA) was measured in seminal plasma and serum of 113 men under investigation for involuntary barrenness. PSA in seminal plasma was 0.4 +/- 0.3 (median 0.35) mg/mL and in serum 0.6 +/- 0.5 (median 0.6) ng/mL. The concentrations in these 2 compartments were independent of each other. The determination of PSA in neither blood serum nor seminal plasma brought new essentials for fertility status.