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Updated: Aug 18, 2026
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
Oxalate in human seminal plasma: possible significance and problems of oxalate determination
M Eiss1, G Schieferstein, R Wahl
1Eberhard-Karls-Universitaet Tübingen, Tübingen, Germany.
Objective:
To determine the level of oxalate in seminal plasma and to correlate it with andrologic variables.
Design:
Laboratory examination.
Setting:
University-based department of andrology and department of clinical chemistry.
Patient(S):
One hundred male outpatients with infertility.
Intervention(S):
Isolated seminal plasma was stored for 120 days at -20 degrees C.
Main Outcome Measure(S):
Levels of oxalic acid in seminal plasma.
Result(S):
Oxalate levels in seminal plasma depend on the degradation of ascorbic acid to oxalic acid during storage. There was a linear nonenzymatic increase of oxalate with storage time. After 120 days of storage, the values were 133 +/- 50 micromol/L (n = 100). Oxalic acid correlated significantly with the number of sperm head anomalies, the pH value, and the age of the donors and correlated negatively with the volume of ejaculate.
Conclusion(S):
Oxalic acid in seminal plasma may influence male fertility.
