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[Gougerot-Sjögren syndrome. Neurologic complications]
Z Amoura1, C Lafitte, J C Piette
1Service de Médecine interne, Hôpital de la Pitié-Salpêtrière, Paris. zahir.amoura@psl.ap-hop-paris.fr
Abstract:
PERIPHERAL NERVE INVOLVEMENT: Peripheral nerve involvement is better known than central nervous system involvement. The dominant features are sensoromotor polyneuropathies or pure sensorial polyneuropathies. CENTRAL NERVOUS SYSTEM: The manifestations are polymorphous, generally presenting as encephalitis and/or focal or multifocal involvement of the spinal cord. OTHER LOCALIZATIONS: Diffuse encephalic involvement is less common: acute aseptic meningitis, intellectual deterioration. Psychiatric manifestations are also frequently observed.
Therapeutic Options:
Response to corticosteroid therapy or immunosuppressor therapy can be spectacular but is unpredictable.