Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic disk appearances in primary open-angle glaucoma.

D C Broadway1, M T Nicolela, S M Drance

  • 1Department of Ophthalmology, University of British Columbia, Vancouver, Canada.

Survey of Ophthalmology
|July 23, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trabeculectomy training in England: are we safe at training? Two year surgical outcomes.

Eye (London, England)·2018
Same author

Rates of glaucomatous visual field change after trabeculectomy.

The British journal of ophthalmology·2016
Same author

Patterns of adherence behaviour for patients with glaucoma.

Eye (London, England)·2013
Same author

Rates of retinal nerve fibre layer thickness change in glaucoma patients and control subjects.

Eye (London, England)·2012
Same author

Primary trabeculectomy with 5-fluorouracil for glaucoma secondary to uveitis.

Ocular immunology and inflammation·2012
Same author

Association between intraocular pressure and adherence: is there one?

Eye (London, England)·2011

Primary open-angle glaucoma (POAG) is multifactorial, influenced by cardiovascular factors and optic nerve head appearance. Subgroups of POAG exist, correlating specific risk factors with distinct optic disk types, aiding clinical diagnosis.

Area of Science:

  • Ophthalmology
  • Cardiovascular Medicine

Background:

  • Primary open-angle glaucoma (POAG) is a complex optic neuropathy.
  • Intraocular pressure and cardiovascular factors are recognized POAG risk factors.
  • Optic nerve head (ONH) appearance may be influenced by these factors.

Purpose of the Study:

  • To investigate potential subgroups of POAG based on optic disk appearance.
  • To identify correlations between demographic characteristics, risk factors, visual field damage, and retrobulbar vascular abnormalities in different ONH appearance groups.

Main Methods:

  • Retrospective analysis of patients with four distinct optic disk appearances.
  • Comparison of demographic data, cardiovascular risk factors, visual field patterns, and retrobulbar vessel circulation.
  • Evaluation of the scanning laser ophthalmoscope (SLO) for objective ONH assessment.

Related Experiment Videos

Main Results:

  • Significant differences identified in demographics, risk factor prevalence, visual field defects, and retrobulbar hemodynamics among the four ONH appearance groups.
  • Evidence supporting the existence of POAG subgroups linked to specific risk factors and ONH morphologies.
  • Scanning laser ophthalmoscopy shows promise for objective differentiation of ONH appearances.

Conclusions:

  • POAG likely comprises distinct subgroups characterized by specific optic disk appearances and associated risk factor profiles.
  • Understanding these subgroups can refine diagnostic approaches and potentially personalize treatment strategies.
  • Objective ONH assessment tools like SLO are crucial for clinical management.