Related Experiment Videos
Deep venous thrombosis in peripheral vascular disease
1Nuffield Department of Surgery, John Radcliffe Hospital, Oxford, UK.
The British Journal of Surgery
|July 27, 1999
Summary
Patients with peripheral vascular disease (PVD) have a high prevalence of deep venous thrombosis. Lower ankle-brachial pressure index (ABPI) independently increases the risk of this condition.
Area of Science:
- Vascular Medicine
- Cardiovascular Research
- Diagnostic Imaging
Background:
- Peripheral vascular disease (PVD) affects lower limb circulation.
- Deep venous thrombosis (DVT) is a significant complication.
- The link between PVD and DVT prevalence requires investigation.
Purpose of the Study:
- To determine the prevalence of lower limb deep venous thrombosis in patients with PVD.
- To identify risk factors associated with DVT in this population.
Main Methods:
- Prospective study involving 136 PVD patients and 40 controls.
- Colour duplex ultrasonography used to screen for DVT.
- Ankle-brachial pressure index (ABPI) and risk factors were recorded.
Main Results:
- DVT found in 27/136 PVD patients vs. 2/40 controls (P=0.03).
- Decreasing ABPI was an independent risk factor for DVT.
- Prevalence of DVT correlated with ischaemia severity.
Conclusions:
- High prevalence of DVT in PVD patients.
- Ischaemia severity, indicated by ABPI, is linked to DVT risk.
- Further research into DVT screening in PVD patients is warranted.