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Sporadic ulcerative-mutilating acropathy of the foot. Features and therapeutic indications
L de Palma1, S Carloni, S Rapali
1Department of Orthopedics, University of Ancona School of Medicine, Italy. ortop@popcsi.unian.it
Abstract:
Ulcerative-mutilating acropathy occurs as an inherited (Thévenard's disease) and a sporadic (Bureau-Barrière syndrome) variant. We report a retrospective study in nine patients with the sporadic variant. All nine had painless foot ulcers with trophic disorders and severe skeletal alterations. Electrodiagnostic testing showed polyneuropathy with sensory disorders in seven patients. Motor conduction velocity was normal. Radiological changes were confined to the lower limbs. The clinical course and treatment of sporadic ulcerative-mutilating acropathy are presented.
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