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Identification of a herpes simplex virus-induced dendrite in an eye-bank donor cornea
M V Neufeld1, T L Steinemann, L M Merin
1Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock 72205-7199, USA.
Cornea
|July 28, 1999
Abstract
Purpose:
To demonstrate the presence of an active herpetic dendrite in an eye-bank cornea.
Case Report:
One eye-bank cornea was studied. Viral cultures and polymerase chain reaction (PCR) testing were performed 4 days after tissue preservation. The presence or absence of herpes simplex virus (HSV) type 1 was investigated.
Results:
The presence of an active HSV dendrite in an eye-bank cornea was verified. HSV type 1 was confirmed using PCR amplification and restriction endonuclease DNA fragment analysis.
Conclusion:
This case suggests that HSV may remain viable in stored corneal tissue at 4 degrees C.