[Disordered cerebral hemodynamics in diabetic patients (based on myelographic data)]

Area of Science:

• Neurology
• Endocrinology
• Vascular Medicine

Background:

• Diabetes mellitus (DM) is a complex metabolic disorder with known systemic complications.
• Cerebrovascular health is crucial for overall patient well-being and can be affected by chronic diseases like DM.

Purpose of the Study:

• To investigate the cerebrovascular system's condition in patients with diabetes mellitus.
• To determine the relationship between diabetes mellitus characteristics and the extent of cerebrovascular disturbances.

Main Methods:

• Examined seventy-six patients diagnosed with diabetes mellitus (aged 16-65).
• Classified patients into insulin-dependent and insulin-nondependent DM, and by disease severity (moderate and severe).
• Assessed cerebrovascular system using rheography, evaluating vasomotor tone, pulse blood filling, and venous hypertension.

Main Results:

• All patients exhibited cerebrovascular system changes, including hypertonic rheograms and increased vasomotor tone.
• Elevated venous pressure and altered pulse blood filling were observed across all vessel sizes.
• The degree of cerebrovascular disturbances was directly related to DM duration, severity, and glycemic control.

Conclusions:

• Diabetes mellitus significantly affects the cerebrovascular system in patients across a wide age range.
• Cerebrovascular disturbances in DM patients are multifactorial, influenced by disease duration, severity, and metabolic compensation.
• These findings highlight the importance of monitoring cerebrovascular health in individuals with diabetes.