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Related Experiment Videos

Shape changes in the cleft palate maxilla: a longitudinal study.

P E Lestrel1, S Berkowitz, O Takahashi

  • 1Section of Oral Biology, University of California-Los Angeles School of Dentistry, USA. plestrel@ucla.edu

The Cleft Palate-Craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
|July 30, 1999
PubMed
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Maxillary shape differences persist in patients with cleft lip and palate (CLP) even after treatment. These shape variations, particularly a posterior repositioning of the nasal crest, are evident in both young and older CLP individuals compared to controls.

Area of Science:

  • Craniofacial morphology
  • Medical imaging analysis
  • Orthodontics

Background:

  • Cleft lip and palate (CLP) is a common congenital condition affecting facial development.
  • Surgical interventions aim to correct anatomical defects, but residual morphological changes may persist.
  • Objective assessment of maxillary shape in treated CLP patients is crucial for understanding long-term outcomes.

Purpose of the Study:

  • To compare the maxillary shape in Norma lateralis between patients with cleft lip and palate (CLP) and non-CLP controls.
  • To identify residual shape changes in the treated maxilla of CLP patients using quantitative methods.
  • To assess these changes in both early and late post-treatment stages.

Main Methods:

  • Utilized longitudinal data from the Miami Craniofacial Anomalies Foundation.

Related Experiment Videos

  • Selected two groups of CLP patients (early and late post-surgery) and matched them with controls.
  • Applied elliptical Fourier functions (EFFs) to digitized lateral cephalometric radiographs to analyze maxillary shape.
  • Standardized outlines for size and corrected for positioning in 2D space.

    • Main Results:

    • Statistically significant maxillary shape differences were found between CLP patients and controls in both young and older groups.
    • No significant gender-based shape differences were observed.
    • Morphological analysis revealed a posterior repositioning of the nasal crest in CLP cases compared to controls.

    Conclusions:

    • Despite clinically satisfactory surgical outcomes, distinct differences in maxillary shape remain in treated CLP patients.
    • The posterior repositioning of the nasal crest is a key morphological characteristic differentiating CLP patients.
    • These findings highlight the need for continued monitoring and potential long-term management strategies for CLP patients.