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Related Experiment Videos

Ruptured primary splenic angiosarcoma into the colon. Presentation as anal bleeding.

J A Jiménez-Heffernan1, D Hardisson, M I Prieto-Nieto

  • 1Department of Pathology, University Hospital La Paz, Madrid, Spain.

Acta Gastro-Enterologica Belgica
|July 31, 1999
PubMed
Summary

Splenic angiosarcoma is a rare and aggressive cancer that is difficult to diagnose preoperatively. This case highlights its challenging presentation and poor prognosis, even with treatment.

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Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Splenic angiosarcoma is a rare vascular tumor with a high propensity for metastasis.
  • Preoperative diagnosis of primary splenic tumors can be challenging due to nonspecific symptoms.

Observation:

  • A 71-year-old woman presented with chronic constipation, abdominal discomfort, and recent anal bleeding.
  • Abdominal imaging revealed a large, heterogeneous mass in the splenic region, with unclear origin.
  • Surgical intervention showed a primary splenic angiosarcoma invading the colon.

Findings:

  • Pathologic examination confirmed primary angiosarcoma of the spleen with colonic fistulization.
  • The patient received adjuvant radiation therapy but developed widespread metastatic disease.

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  • Death occurred nine months post-surgery due to extensive metastatic angiosarcoma.

    • Implications:

    • Splenic angiosarcoma presents diagnostic challenges, often mimicking other abdominal pathologies.
    • Early detection and prompt treatment are crucial for improving outcomes in splenic angiosarcoma.
    • This case underscores the aggressive nature and poor prognosis associated with splenic angiosarcoma, especially with rupture.