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Synthesis and antiviral activity of L-2'-deoxy-2'-up-fluoro-4'-thionucleosides
Nucleosides & Nucleotides
|August 5, 1999
Abstract:
L-2'-Deoxy-2'-up-fluoro-4'-thionucleosides were efficiently synthesized from D-xylose via L-4-thioarabitol derivative as a key intermediate and evaluated for antiviral activities against HIV-1, HSV-1,2 and HBV.