A new cyclic phosphoramidate D4T prodrug approach cycloAmb-D4T-phosphoramidates

¹Institut für Organische Chemie, Universität Hamburg, Germany.

Nucleosides & Nucleotides

|August 5, 1999

Abstract:

A new potential phosphoramidate prodrug approach for d4T 1 is described. In hydrolyses studies the cycloAmb-d4T-phosphoramidates 2 and 3 proved to deliver d4TMP following a tandem reaction.

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Abstract:

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