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Bicyclonucleosides and ring-chain interconversion
J M Tronchet1, M Zsély, L Brenas
1University of Geneva, Department of Pharmaceutical Chemistry, Switzerland.
Abstract:
Four types of bicyclonucleosides differing in the easiness of their ring-chain interconversion have been prepared, some exhibited anti-HIV activity and the ratio of their cyclic and open-chain forms could have some bearing on their biological activity.