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Haemodynamic changes after tracheal intubation in cigarette smokers compared with non-smokers
C H Laxton1, Q Milner, P J Murphy
1Royal Devon and Exeter Hospital, Wonford, UK.
British Journal of Anaesthesia
|August 6, 1999
Summary
Smokers experienced a significantly higher heart rate immediately after tracheal intubation compared to non-smokers. This finding is crucial for understanding cardiovascular risks in smokers undergoing surgery.
Area of Science:
- Anesthesiology
- Cardiovascular Physiology
Background:
- Tracheal intubation can trigger significant hemodynamic responses.
- Smoking is a known risk factor for cardiovascular disease.
Purpose of the Study:
- To investigate the impact of smoking on hemodynamic changes following tracheal intubation.
- To compare the heart rate response to intubation between smokers and non-smokers.
Main Methods:
- Studied 60 American Society of Anesthesiologists (ASA) I women undergoing elective gynecological surgery.
- Divided participants into two groups: 30 smokers (≥10 cigarettes/day) and 30 non-smokers.
- Measured heart rate immediately after tracheal intubation.
Main Results:
- Smokers exhibited a significantly higher mean heart rate (102.0 bpm) post-intubation compared to non-smokers (91.0 bpm).
- The difference in heart rate was statistically significant (P < 0.01).
Conclusions:
- Tracheal intubation elicits a more pronounced heart rate increase in smokers.
- These findings highlight potential cardiovascular risks for smokers undergoing surgical procedures and warrant further investigation.