[Heterotopic adipose tissue in the uterine cervix]

Lipomatous lesions of the uterus are uncommon and the few cases reported only describe those lesions associated with neoplasia of the soft tissue such as leiomyomas, or pure, characterizing lipomas, and there are no reports on the diffuse or neoplastic form. A 34-year-old woman, para 1, abortion 1, presented with discrete leukorrhea without other complaints. On speculum examination, polypoid papillary ectopia was observed macroscopically which may have been caused by epithelial hyperplasia due to papillomavirus infection or the use of anovulatory drugs. Histologic examination revealed diffuse infiltration of the endocervical stroma by mature adipocytes, characterizing choristoma. The patient did not receive any treatment and was found to be well 2 years after a biopsy. The presence of mature heterotopic non-neoplastic adipose tissue in the uterine cervix has not been previously reported. The histogenesis of the lesion has not been defined; however, the hypothesis has been raised that smooth muscle cells of the cervical stroma are directly transformed into adipocytes, as demonstrated by immuno-histochemical analysis.