Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Congenital malformations in twins].

J Nazer1, L Cifuentes, M Bazzano

  • 1Unidad de Neonatología, Hospital Clínico Universidad de Chile, Santiago, Chile.

Revista Medica De Chile
|August 7, 1999
PubMed
Summary

Congenital malformations were not more frequent in liveborn twins compared to singletons. However, stillborn twins showed a significantly higher prevalence of malformations than stillborn singletons.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emotional states in patients with cancer or with suspected oral potentially malignant disorders: a cross-sectional study in an oral medicine setting.

Medicina oral, patologia oral y cirugia bucal·2025
Same author

Parafunctional habits and attitude to oral health reported by students attending public middle schools in the South of Italy.

European journal of paediatric dentistry·2025
Same author

Salivary analysis to unveil the paradigma of stress of domestic horses reared in the wild.

Scientific reports·2024
Same author

Reducing the anxiety of patients undergoing an oral biopsy by means of graphic novels: an open-label randomized clinical trial.

Medicina oral, patologia oral y cirugia bucal·2023
Same author

Isolation of extracellular vesicles from bitch's amnion-derived cells culture and their CD59 expression: Preliminary results.

Theriogenology·2023
Same author

The Chilean socio-ethno-genomic cline.

Biodemography and social biology·2021

Area of Science:

  • Perinatology
  • Genetics
  • Public Health

Context:

  • Previous literature suggests a higher prevalence of congenital malformations in twins compared to singletons.
  • This study investigates congenital malformation incidence in twins within a specific South American maternity hospital.
  • The study period spanned 15 years (1983-1997).

Purpose:

  • To determine the incidence of congenital malformations in twin births.
  • To compare malformation rates between twins and singletons.
  • To identify specific malformations and their potential causes in twin gestations.

Summary:

  • A 15-year study of 48,663 single and 448 twin pregnancies found similar malformation rates in liveborn twins (7.1%) and singletons (6.5%).
  • However, stillborn twins exhibited a significantly higher malformation rate (35.2%) compared to stillborn singletons (17.2%).
  • Specific malformations associated with monozygotic twinning and uterine compression were observed in some twin pairs.

Impact:

  • Highlights a critical difference in malformation prevalence between liveborn and stillborn twins.
  • Suggests that stillbirth in twins may be linked to a higher burden of congenital anomalies.
  • Provides valuable data for understanding twin-specific risks and improving perinatal care in multiple gestations.

Related Experiment Videos