Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Multiple mononeuropathy and vasculitis].

L Cartier1, M García, P Peñaherrera

  • 1Departamento de Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile, Santiago-Chile.

Revista Medica De Chile
|August 7, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recurrent supplementary motor area syndrome in relapsed parasagittal meningiomas: from the onset to the origin.

Neurologia·2019
Same author

[Causes, diagnosis and treatments of circulatory shocks].

La Revue de medecine interne·2019
Same author

Development of liquid chromatography tandem mass spectrometry method to quantify cyclobutane pyrimidine dimer photolyase activity by detection of 15mer oligonucleotide as reaction product.

Journal of chromatography. A·2019
Same author

Severity of Candida-associated denture stomatitis is improved in institutionalized elders who consume Lactobacillus rhamnosus SP1.

Australian dental journal·2019
Same author

Genetic basis for variation in plasma IL-18 levels in persons with chronic hepatitis C virus and human immunodeficiency virus-1 infections.

Genes and immunity·2017
Same author

Improved hybrid/GPU algorithm for solving cardiac electrophysiology problems on Purkinje networks.

International journal for numerical methods in biomedical engineering·2016
Same journal

[Health Education for Informed Autonomy: When to Begin?]

Revista medica de Chile·2026
Same journal

[Open Atrial Transcatheter Mitral Valve Replacement for Mitral Annular Calcification: First Case Report in Chile].

Revista medica de Chile·2026
Same journal

[From Opinion to Structure: The Role of Different Types of Systematic Reviews Within the Evidence Synthesis Ecosystem].

Revista medica de Chile·2026
Same journal

[Neuropsychiatric Effects of Creatine: What Does the Preclinical and Clinical Evidence Conclude?]

Revista medica de Chile·2026
Same journal

[Ethical Issues in Early Serological Diagnosis of Alzheimer's Disease].

Revista medica de Chile·2026
Same journal

[Weight Recurrence After Bariatric Surgery: Definitions, Diagnosis, and Management Strategies. Part 1].

Revista medica de Chile·2026
See all related articles

Vasculitis commonly affects nerves, causing multiple mononeuropathy (MM) or asymmetrical neuropathy (AN). Superficial peroneal nerve biopsy is highly diagnostic for vasculitis-associated MM or AN, with nerve and muscle biopsies offering complementary diagnostic value.

Area of Science:

  • Neurology
  • Pathology
  • Vascular Biology

Context:

  • Neurological manifestations of vasculitis often present as multiple mononeuropathy (MM) or asymmetrical neuropathy (AN).
  • Accurate diagnosis of vasculitis relies on identifying pathological vascular changes in affected tissues.

Purpose:

  • To define the pathological features of vascular damage in nerve and muscle tissue in patients diagnosed with MM or AN.
  • To evaluate the diagnostic utility of concurrent nerve and muscle biopsies in vasculitis.

Summary:

  • A study of 50 patients with MM or AN revealed 42 had vasculitis, predominantly necrotizing arteritis affecting nerve biopsies in 87% of cases.
  • While nerve biopsies were highly diagnostic, muscle biopsies showed neurogenic atrophy and microinfarcts, indicating complementary diagnostic information.

Related Experiment Videos

  • Vascular recanalization was observed in 33% of cases, and inflammatory changes were noted in both large and small epineural arteries.

    • Impact:

    • Superficial peroneal nerve biopsy is confirmed as a key diagnostic tool for vasculitis-associated MM or AN.
    • Combined nerve and muscle biopsy enhances diagnostic accuracy, aiding in the comprehensive workup of neuropathies.
    • Findings contribute to understanding the pathological spectrum of vasculitis in neurological conditions.