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[Clinical values of Pseudomonas corneal ulcer treated by lamellar keratoplasty]
1Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou.
Objective:
The study was designed to explore the pathological mechanisms and effective methods of treatment for pseudomonas corneal ulcer.
Method:
The nearly perforating pseudomonas corneal ulcer was treated by lamellar keratoplasty and the corneal bottoms were studied histopathologically.
Results:
21 cases 21 eyes with pseudomonas corneal ulcers were treated by lamellar keratoplasty, the corneal contour was recovered successfully and a good optical outcome was attained. The study revealed that in the disease not only there was the corneal violent inflammatory reaction, but also there was a large amount of immune cells in the limbal bulbar conjunctiva, sclera, surroundings and base of corneal ulcer. The corneal collagen was degenerative and neovascular vessels invaded the lesion.
Conclusions:
Possibly, both the inflammatory and immune reactions exist in the pathological mechanisms of the pseudomonas corneal ulcer. The pathological processes can be stopped by lamellar keratoplasty and a better clinical outcome can be attained.
