Following the learning curve: the evolution of kinder, gentler neonatal respiratory technology

Immense progress has been made in all aspects of neonatal critical care during the past 4 decades, particularly in the realm of respiratory support. A historical overview of the evolution of neonatal respiratory support illustrates how technological advances are improving survival and outcome for many sick newborns. Major milestones in this history include continuous positive airway pressure, conventional ventilation, exogenous surfactant, extracorporeal membrane oxygenation, and high frequency ventilation. Changes in clinical and nursing care highlight the significant impact of technological and practice advances on neonatal respiratory morbidity. Although bronchopulmonary dysplasia still occurs, the incidence and severity have decreased. The nature and outcome of the neonatal intensive-care experience has been redefined for many infants; however, great challenges remain in the care of infants on the edge of viability.