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Angina bullosa hemorrhagica.
D Grinspan1, J Abulafia, H Lanfranchi
1Department of Dermatology, Hospital de Clínicas, University of Buenos Aires School of Medicine, Argentina.
International Journal of Dermatology
|August 10, 1999
Summary
Angina bullosa hemorrhagica (ABH) is more common than previously thought, often affecting adults over 50. Altered glucose metabolism, including diabetes, is frequently associated with this oral condition.
Area of Science:
- Oral Medicine
- Pathology
Background:
- Angina bullosa hemorrhagica (ABH) is a condition with a complex nomenclature history, previously known as traumatic oral hemophlyctenosis (TOH) and recurrent oral hemophlyctenosis (ROH).
- This study aims to clarify the understanding of ABH by reviewing existing literature and presenting new case data.
Purpose of the Study:
- To review and discuss the literature on Angina bullosa hemorrhagica (ABH).
- To report on 54 new cases of ABH observed between 1989 and 1996.
- To analyze the clinical features, etiology, pathogenesis, and treatment of ABH.
Main Methods:
- A thorough assessment of 54 patients diagnosed with ABH.
- Evaluation of clinical presentation, histological findings, and patient history.
- Analysis of potential contributing factors including trauma, medication use, and metabolic status.
Main Results:
- Lesions predominantly occurred on the palate (64.8%) and oral mucosa (16.6%).
- The condition affected all age groups, with a peak incidence in the 51-70 year age range, and was not observed in children under 10.
- A significant association was found with diabetes mellitus, hyperglycemia, or a family history of diabetes in 44.4% of cases.
- The incidence was nearly equal between sexes (52% female, 48% male).
Conclusions:
- Angina bullosa hemorrhagica (ABH) is likely more prevalent than current literature suggests.
- Potential causes include mucosal trauma and inhaled corticosteroids.
- A strong correlation exists between ABH and alterations in glucose metabolism, warranting consideration of diabetes screening in affected individuals.