Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Melanoma on dysplastic nevus spilus

D Grinspan1, A Casala, J Abulafia

  • 1Department of Dermatology, Hospital de Clínicas José de San Martin, University of Buenos Aires, Argentina.

International Journal of Dermatology
|July 1, 1997
PubMed
Summary

Nevus spilus, a common skin condition, can rarely develop into malignant melanoma. Close monitoring of these lesions is crucial for early detection and improved patient outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply.

Journal of the American Academy of Dermatology·2017
Same author

Leprosy: accessory immune system as effector of infectious, metabolic, and immunologic reactions.

International journal of dermatology·2001
Same author

[Ulcerated cutaneous lymphoma. 10 years of experience].

Medicina·2001
Same author

Heterogeneous distribution of tumor blood supply affects the response to chemotherapy in patients with head and neck cancer.

Microcirculation (New York, N.Y. : 1994)·2001
Same author

Degenerative collagenous plaques of the hands and acrokeratoelastoidosis: pathogenesis and relationship with knuckle pads.

International journal of dermatology·2000
Same author

Prevalence of cutaneous manifestations in 200 patients with eating disorders.

International journal of dermatology·2000

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Nevus spilus presents as a tan to brown macule with darker maculo-papular elements.
  • While relatively common, nevus spilus carries a rare risk of malignant transformation into melanoma.

Observation:

  • This study reviewed 17 cases of nevus spilus with associated melanoma, including a unique case presentation.
  • Patients were predominantly Caucasian, aged 35-56, with lesions typically on the dorsal region.

Findings:

  • Congenital nevus spilus lesions, 2-10 cm in diameter, were common.
  • Histological analysis revealed junctional nevi with some dysplastic characteristics; melanomas were primarily of the superficial spreading type.
  • Metastases were observed in some cases, with a mortality rate of three patients.

Related Experiment Videos

Implications:

  • The findings underscore the importance of vigilant monitoring for nevus spilus.
  • Early detection of malignant changes in nevus spilus can significantly impact prognosis and patient survival.