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Zinc, exercise, and thyroid hormone function.

S Ganapathy1, S L Volpe

  • 1University of Massachusetts, Dept. of Nutrition, Chenoweth Lab, Amherst 01003-1420, USA.

Critical Reviews in Food Science and Nutrition
|August 12, 1999
PubMed
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Zinc is essential for human health, with over 200 enzymes requiring it. This review explores the complex relationship between zinc status, exercise, and thyroid hormone function, highlighting the challenges in assessing zinc levels.

Area of Science:

  • Biochemistry
  • Human Nutrition
  • Endocrinology

Background:

  • Zinc metabolism research has advanced significantly, identifying over 200 zinc-dependent enzymes.
  • Zinc deficiency, once unrecognized in humans, is now a global concern, affecting populations worldwide.
  • Assessing zinc status remains challenging due to the lack of reliable biomarkers.

Purpose of the Study:

  • To review the current understanding of zinc's role in human nutrition and biochemical functions.
  • To explore the emerging evidence linking zinc status to thyroid hormone metabolism.
  • To examine the impact of exercise on zinc status and its implications.

Main Methods:

  • Literature review focusing on studies investigating zinc metabolism, deficiency, and status assessment.

Related Experiment Videos

  • Analysis of research on the interaction between zinc and thyroid hormones.
  • Examination of studies examining exercise-induced alterations in zinc status.

    • Main Results:

    • Zinc is crucial for numerous biochemical processes, with deficiency being prevalent globally.
    • Emerging research suggests a role for zinc in thyroid hormone metabolism, though mechanisms are unclear.
    • Exercise demonstrably affects zinc status, necessitating further investigation into its effects.

    Conclusions:

    • Despite advances, accurate assessment of human zinc status remains a significant challenge.
    • Further research is needed to elucidate the precise mechanisms of zinc's influence on thyroid hormone function.
    • Understanding the interplay between zinc, exercise, and thyroid hormones is critical for public health and athletic performance.