Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human fetuses have nonlinear cardiac dynamics.

L J Groome1, D M Mooney, S B Holland

  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of South Alabama, Mobile, Alabama 36604, USA. lgroome@jaguar1.usouthal.edu

Journal of Applied Physiology (Bethesda, Md. : 1985)
|August 13, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts.

Frontiers in cell and developmental biology·2021
Same author

Applications of novel bioreactor technology to enhance the viability and function of cultured cells and tissues.

Interface focus·2020
Same author

Ubiquitous parasites drive a 33% increase in methane yield from livestock.

International journal for parasitology·2018
Same author

To fill or not to fill: a qualitative cross-country study on dentists' decisions in managing non-cavitated proximal caries lesions.

Implementation science : IS·2018
Same author

Can BAPEN do more to advance nutrition training amongst trainee doctors? Results of the first UK BAPEN medical trainee group survey.

Clinical nutrition ESPEN·2017
Same author

Viral Carcinogenesis.

Progress in molecular biology and translational science·2016

Approximate entropy (ApEn) analysis reveals nonlinear patterns in fetal heart rate (HR). Fetal HR time series data differ significantly from noise models, indicating unique physiological complexity.

Area of Science:

  • Physiology
  • Biomedical Engineering
  • Nonlinear Dynamics

Background:

  • Approximate entropy (ApEn) quantifies time series regularity, valuable for physiological data analysis.
  • Understanding fetal heart rate (HR) patterns is crucial for assessing fetal well-being.

Purpose of the Study:

  • To detect nonlinearities in the heart rate (HR) patterns of low-risk human fetuses.
  • To assess if fetal HR time series can be modeled by various noise and linear models.

Main Methods:

  • ApEn was applied to HR time series from 12 fetuses (38-40 wk gestation).
  • Fetal R waves were extracted from ECG signals using adaptive signal processing.
  • ApEn of original HR data was compared against three dynamic models (uncorrelated noise, linearly correlated noise, nonlinear distortion).

Related Experiment Videos

Main Results:

  • Noise accounted for 17.2-44.5% of between-fetus variance in ApEn.
  • Original fetal HR time series ApEn significantly differed from all three dynamic models.
  • These differences were observed in both group comparisons and individual fetuses.

Conclusions:

  • Fetal HR time series in low-risk fetuses exhibit nonlinear characteristics.
  • Fetal HR cannot be adequately modeled as simple uncorrelated or linearly correlated noise.
  • The findings suggest inherent complexity in the fetal cardiac electrical activity.