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Multi-step evolution of lung cancer
K L Braithwaite1, P H Rabbitts
1MRC Molecular Oncology Group, Department of Oncology, MRC Centre, University of Cambridge, Hills Road, CB2 2QH, UK.
Seminars in Cancer Biology
|August 17, 1999
Abstract:
In an attempt to improve the poor survival rates for lung cancer, therapeutic strategies require a deeper understanding of the biological events contributing to the formation and progression of the disease. In particular, the importance of studying the different stages of lung cancer including early pre-neoplasia is being recognised and studies examining genetic changes in pre-invasive and invasive lesions are being used to identify key events in tumorigenesis.