Related Experiment Video
Updated: Oct 9, 2026

Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging
Published on: March 17, 2020
Clinical application of markers of cardiac injury: basic concepts and new considerations
1Jewish Hospital Heart and Lung Institute, Louisville, KY 40202, USA. jadams03@sprynet.com
Abstract:
Cardiac markers have progressed from measurement of enzymes such as serum glutamate oxaloacetate transaminase and creatine kinase isoenzymes to structural proteins such as cardiac troponin. The utility of biomarkers have evolved from diagnosis of cardiac injury to assessment of the prognosis of patients with unstable angina. While cardiac angiography can serve as the gold standard for coronary anatomy, it is inadequate for detecting active myocardial damage. The finding of a typical rising and falling pattern of a highly specific biochemical marker in blood such as cardiac troponin will likely be the best indicator for detection of myocardial cell necrosis.
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