Related Experiment Video
Updated: Aug 14, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
Decisional balance regarding substance use among persons with schizophrenia
K B Carey1, D M Purnine, S A Maisto
1Department of Psychology, Syracuse University, NY 13244-2340, USA. kbcarey@syr.edu
Abstract:
State-of-the-science treatment of substance abuse relies on decisional balance activities (weighing pros and cons of continued substance use) to enhance motivation for change. Few data are available regarding the feasibility of these activities among persons dually diagnosed with schizophrenia and substance use disorder. To address this lacuna in the literature, we completed focus groups with 21 participants, all of whom had a schizophrenia-spectrum diagnosis and lifetime substance abuse or dependence. These key informants discussed the pros and cons of substance use as well as the pros and cons of quitting in response to a structured group interview. Our qualitative data indicate that persons living with schizophrenia can generate rich and diverse decisional balance information. We describe salient themes, contrast complementary perspectives (i.e., the pros of using and cons of quitting), and suggest treatment implications based on these findings.
Related Concept Videos
Drug Dependence
Psychosis and Antipsychotic Drugs: Overview
Psychosis: Goals of Pharmacotherapy
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Drug Therapy
Antianxiety Medications

