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Analytical Techniques for Assaying Nitric Oxide Bioactivity
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Analytical Techniques for Assaying Nitric Oxide Bioactivity

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Estradiol effects on nitric oxide synthase expression in the rat aorta allograft

S Saito1, M L Foegh, P W Ramwell

  • 1Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical University, Japan.

Transplantation Proceedings
|August 24, 1999
PubMed
Abstract

No abstract available in PubMed .

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Nitric Oxide Signaling Pathway01:28

Nitric Oxide Signaling Pathway

Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure to...

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