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Histopathologic study of presumed parafoveal telangiectasis
1Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Purpose:
To report the postmortem histopathologic features that closely resemble the clinical features of parafoveal telangiectasis.
Methods:
Light and electron microscopy.
Results:
Histopathologic features included macular edema; telangiectatic vessels; retinal, subretinal, and superficial retinal neovascularization; retinal pigment epithelial hyperplasia around neovascular aggregates; retinal-choroidal vascular anastomosis; and superficial pigmented cells with lipofuscin.
Conclusion:
The postmortem histopathologic findings in a 36-year-old woman with Down syndrome and other systemic conditions correlate with features noted in previous reports of presumed parafoveal telangiectasis.