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MR urography: the future gold standard in paediatric urogenital imaging?
A Borthne1, T Nordshus, T Reiseter
1Department of Paediatric Radiology, Ullevaal University Hospital, N-0407 Oslo, Norway.
Insights
Magnetic resonance urography (MRU) shows promise in diagnosing paediatric urinary tract conditions, potentially replacing radiation-based imaging. Further research is needed to confirm its effectiveness and establish definitive conclusions.
Area of Science:
- Medical Imaging
- Paediatric Radiology
- Urology
Background:
- Traditional paediatric urogenital tract examinations often involve ionizing radiation (IVU, CT, VCU, scintigraphy) alongside ultrasound (US).
- There is a need for alternative diagnostic methods that minimize radiation exposure in children.
Purpose of the Study:
- To evaluate the potential and effectiveness of Magnetic Resonance Urography (MRU) for diagnosing infants and children with urinary tract pathologies.
- To compare MRU with traditional methods, particularly scintigraphy, in cases of suspected urinary tract obstruction.
Main Methods:
- Prospective study of 44 MRU examinations in 39 paediatric patients (21 infants, 18 children) with suspected urinary tract issues.
- Utilized non-enhanced fast spin-echo (TSE) sequences in all patients, with contrast-enhanced fast gradient-echo (TFE) sequences in 70%.
- Included prolonged dynamic sequences and furosemide provocation in select cases of suspected obstruction.
Main Results:
- MRU was non-diagnostic or interrupted in 9% of examinations due to patient movement.
- MRU provided additional diagnostic information in 66% of cases.
- In suspected obstruction, contrast-enhanced MRU was comparable or superior to scintigraphy when employing prolonged dynamic sequences with furosemide provocation.
Conclusions:
- MRU demonstrates potential as a non-ionizing radiation alternative for paediatric urinary tract imaging.
- Further investigation is required to solidify MRU's role and draw definitive conclusions regarding its diagnostic superiority.
Background:
Examination of the paediatric urogenital tract is traditionally performed using methods that utilise ionising radiation, such as intravenous urography (IVU), computerised tomography (CT), voiding cystourethrography (VCU), and scintigraphy, in addition to ultrasound (US).
Objective:
To determine the potential and effectiveness of MR urography (MRU) in infants and children. Materials and methods. 44 MRU examinations were prospectively performed in 39 patients (21 infants, mean age 3.5 months, and 18 children, mean age 6 years 2 months) with known or suspected pathology of the urinary tract. Non-enhanced, fast spin-echo sequences (TSE) were performed in all patients. In 70 % of the patients a contrast-enhanced, fast gradient-echo sequence (TFE) was included. The dynamic sequence was prolonged and supplemented with furosemide provocation in some patients with suspected urinary-tract obstruction.
Results:
Nine percent of examinations were non-diagnostic or interrupted due to movement. MRU contributed additional information in 66 %. Nine patients with suspected urinary-tract obstruction were examined with both contrast-enhanced MRU and scintigraphy. Three MRU examinations were less informative and one equal to scintigraphy when obstruction was the diagnosis. When using a technique with a prolonged dynamic sequence, including frusemide provocation, four MRU examinations were equal and one was superior to scintigraphy.
Conclusions:
MRU has the potential to replace traditional diagnostic methods which use ionising radiation in paediatric patients. Further studies are needed before definite conclusions can be drawn.
Related Concept Videos
Imaging Studies I: Kidney, Ureter, and Bladder Studies
Imaging Studies II: Ultrasonography
Imaging Studies III: Computed Tomography
Imaging Studies IV: Magnetic Resonance Imaging
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VI: Voiding Cystourethrography and Cystography

