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Subcutaneous Administration of Muscarinic Antagonists and Triple-Immunostaining of the Levator Auris Longus Muscle in Mice
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Muscle relaxant activity of methocarbamol enantiomers in mice

E Souri1, M Sharifzadeh, H Farsam

  • 1Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Iran.

The Journal of Pharmacy and Pharmacology
|September 1, 1999
PubMed

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Classification of Skeletal Muscle Relaxants

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Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
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Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx as...
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Centrally Acting Muscle Relaxants: Therapeutic Uses

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