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Severe oral ulcerations induced by alendronate
N Demerjian1, G Bolla, A Spreux
1Service de Médecine et Rheumatologie, Hôpital de Cannes, France.
Clinical Rheumatology
|September 1, 1999
Summary
Misusing alendronate tablets by sucking them instead of swallowing caused severe oral ulcerations in a patient with steroid-induced osteoporosis. This case highlights the risk of direct mucosal injury from improper bisphosphonate use.
Area of Science:
- Pharmacology
- Gastroenterology
- Endocrinology
Background:
- Osteoporosis is a common condition, often treated with bisphosphonates like alendronate.
- Steroid-induced osteoporosis requires careful management to prevent fractures.
Observation:
- A 54-year-old man with steroid-induced osteoporosis presented with severe oral ulcerations.
- The patient admitted to sucking alendronate tablets instead of swallowing them.
Findings:
- Improper administration of alendronate led to direct mucosal injury.
- Oral ulcerations were a direct consequence of the drug's local contact.
Implications:
- Patient education on correct medication use is crucial for bisphosphonates.
- Healthcare providers must emphasize proper alendronate administration to prevent adverse events.
- This case underscores the importance of adherence to medication guidelines to avoid drug-induced injuries.