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Related Experiment Videos

Growth hormone and exercise.

P J Jenkins1

  • 1Department of Endocrinology, St Bartholomew's Hospital, London, UK.

Clinical Endocrinology
|September 1, 1999
PubMed
Summary
This summary is machine-generated.

Exercise significantly impacts the growth hormone (GH)/IGF-I axis, potentially influencing training responses. However, the benefits of GH administration for exercise performance and strength remain unproven in deficient adults and athletes.

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Area of Science:

  • Endocrinology
  • Exercise Physiology
  • Sports Science

Background:

  • The growth hormone (GH)/IGF-I axis plays a crucial role in physiological regulation.
  • Exercise is known to induce significant perturbations in the GH/IGF-I system.
  • Understanding these interactions is vital for both clinical and performance contexts.

Purpose of the Study:

  • To review the complex interactions between growth hormone (GH) and exercise.
  • To evaluate the influence of exercise-induced physiological changes on training adaptations.
  • To assess the efficacy of recombinant human GH (rGH) in clinical and athletic settings.

Main Methods:

  • Literature review of studies investigating GH and exercise.
  • Analysis of physiological responses to exercise concerning the GH/IGF-I axis.

Related Experiment Videos

  • Examination of evidence regarding GH administration for GH deficiency and athletic doping.

    • Main Results:

    • Exercise profoundly affects the GH/IGF-I axis.
    • Physiological changes from exercise may influence performance in repeated training.
    • Evidence for rGH in restoring exercise capability or providing ergogenic benefits is currently lacking.

    Conclusions:

    • The relationship between GH and exercise is multifaceted, impacting physiological function and training.
    • The ergogenic potential of GH doping and its role in GH deficiency require further investigation.
    • These topics are of growing importance for clinical endocrinologists and sports medicine professionals.