Related Experiment Video
Updated: Aug 18, 2026

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Raising eyebrows with botulinum toxin
S C Huilgol1, A Carruthers, J D Carruthers
1Department of Medicine, Vancouver Hospital and Health Sciences Center, Canada.
Background:
Brow elevation rejuvenates the facial appearance.
Objective:
To determine if a significant degree of brow elevation could be achieved through selective botulinum toxin treatment of brow depressors.
Methods:
Seven women aged 31-42 (mean 37) years old were treated. The distance from lowest eyebrow cilium of the eyebrow to the midpupillary point was measured before and 1 month posttreatment. Botulinum toxin was injected into the glabellar area (7-10U) and the supralateral eyebrow (0-2.5U each side), to a total dose of 10-14 U.
Results:
Five individuals (71%) showed brow elevation of 1-3 mm with a mean elevation of 1 mm. Two individuals showed no change. Concurrent weakening of the frown response was noted in all patients.
Conclusion:
Botulinum toxin treatment of brow depressors produces a small degree of brow elevation in the majority of patients.
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