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Related Experiment Videos

Human therapeutic cloning.

R P Lanza1, J B Cibelli, M D West

  • 1Tissue Engineering and Transplant Medicine, Advanced Cell Technology, One Innovation Drive, Worcester, Massachusetts 01605, USA. rlanza@advancedcell.com

Nature Medicine
|September 2, 1999
PubMed
Summary
This summary is machine-generated.

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Somatic cell nuclear reprogramming is a routine technique in livestock. This method may soon enable cloning of genetically matched cells and tissues for transplantation in patients with tissue loss or dysfunction.

Area of Science:

  • Biotechnology
  • Reproductive Biology
  • Cellular Medicine

Background:

  • Somatic cell nuclear reprogramming is established in livestock.
  • Tissue loss and dysfunction affect numerous patients.

Purpose of the Study:

  • To discuss the potential clinical applications of somatic cell nuclear reprogramming.
  • To explore the use of cloned cells and tissues for regenerative medicine.

Main Methods:

  • Review of current somatic cell nuclear reprogramming techniques.
  • Discussion of potential future applications in transplantation.

Main Results:

  • Somatic cell nuclear reprogramming is a well-established technique in livestock.
  • The potential exists for therapeutic cloning to generate patient-specific tissues.
Keywords:
Biomedical and Behavioral ResearchGenetics and Reproduction

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Conclusions:

  • Somatic cell nuclear reprogramming techniques are advancing rapidly.
  • Therapeutic cloning holds promise for treating disorders involving tissue loss or dysfunction.