Related Experiment Videos
Does formate reduce alpha-ketoglutarate and ammonia to glutamate?
1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla 92093-0506, USA.
Abstract:
The reported reduction of alpha-ketoglutarate and ammonia by formate is much slower than described (Morowitz et al., 1995). The formate reduction if any is small under these conditions. Glutamate is produced from a reduction by a second molecule of alpha-ketoglutarate involving an oxidative decarboxylation.