Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Directed molecular evolution.

L F Harris1, M R Sullivan, D L Hatfield

  • 1David F. Hickok Memorial Cancer Research Laboratory, Abbott Northwestern Hospital, Minneapolis, MN 55407, USA. harrislf@sp.msl.umn.edu

Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life
|September 3, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of activated partial thromboplastin time (aPTT) reagents for application in biomedical diagnostic device development.

International journal of laboratory hematology·2010
Same author

Analysis of selenocysteine-containing proteins.

Current protocols in protein science·2008
Same author

Evaluation of cranberry tablets for the prevention of urinary tract infections in spinal cord injured patients with neurogenic bladder.

Spinal cord·2008
Same author

Hormonal responses to a 160-km race across frozen Alaska.

British journal of sports medicine·2007
Same author

Unusual stress fractures of the proximal phalanx of the great toe: a report of two cases.

British journal of sports medicine·2004
Same author

Selenocysteine incorporation directed from the 3'UTR: characterization of eukaryotic EFsec and mechanistic implications.

BioFactors (Oxford, England)·2001
Same journal

Decorated Vesicles as Prebiont Systems (a Hypothesis).

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·2023
Same journal

Enhancement of Prebiotic Peptide Formation in Cyclic Environments.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·2023
Same journal

Sequential Amplification of Amino Acid Enantiomeric Excess by Conglomerate and Racemic Compound: Plausible Prebiotic Route Towards Homochirality.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·2023
Same journal

Did Salts in Seawater Play an Important Role in the Adsorption of Molecules on Minerals in the Prebiotic Earth? The Case of the Adsorption of Thiocyanate onto Forsterite-91.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·2023
Same journal

The Possible Role of Anoxic Alkaline High Subcritical Water in the Formation of Ferric Minerals, Methane and Disordered Graphitic Carbon in a BARB3 Drilled Sample of the 3.4 Ga Buck Reef Chert.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·2023
Same journal

Parity Violation Energy Difference Calculation of Atropisomers.

Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life·2023
See all related articles

We propose stereochemical complementarity between interacting biomolecules, influencing DNA sequence evolution. This suggests a broader "life code" beyond the genetic code, governing biological interactions.

Area of Science:

  • Molecular Biology
  • Evolutionary Biology
  • Biochemistry

Background:

  • Interactions between biomolecules (DNA, RNA, proteins) are fundamental to life.
  • The genetic code translates nucleotide sequences into amino acid sequences.
  • The evolutionary origins of these interactions remain incompletely understood.

Purpose of the Study:

  • To propose a stereochemical complementarity relationship between interacting biomolecular sequences.
  • To explore the evolutionary implications of this proposed relationship.
  • To suggest that this complementarity forms a broader
  • life code
  • governing biological interactions.

Main Methods:

  • Theoretical proposal based on existing biochemical and evolutionary principles.

Related Experiment Videos

  • Analysis of sequence relationships in nucleic acid-nucleic acid, protein-protein, and protein-nucleic acid interactions.
  • Postulation of prebiotic synthesis and evolutionary conservation mechanisms.

    • Main Results:

    • A proposed stereochemical complementarity exists between gene sequences coding for interacting biomolecules.
    • This complementarity imposes evolutionary constraints on DNA sequences.
    • This relationship suggests a regulatory apparatus formed during early life evolution.

    Conclusions:

    • The proposed stereochemical complementarity between interacting biomolecular sequences is a key evolutionary driver.
    • This relationship implies a comprehensive "life code" encompassing the genetic code and other molecular interactions.
    • Understanding this code is crucial for comprehending the evolution and regulation of life.