Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Marginal modelling of multivariate categorical data.

G Molenberghs1, E Lesaffre

  • 1Biostatistics, Limburgs Universitair Centrum, B3590 Diepenbeek, Belgium. geert.molenberghs@luc.ac.be

Statistics in Medicine
|September 4, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sick leave due to SARS-CoV-2 infection.

Occupational medicine (Oxford, England)·2023
Same author

Geographical variation of COVID-19 vaccination coverage, ethnic diversity and population composition in Flanders.

Vaccine: X·2022
Same author

Aligning Estimators With Estimands in Clinical Trials: Putting the ICH E9(R1) Guidelines Into Practice.

Therapeutic innovation & regulatory science·2020
Same author

Generalized pairwise comparison methods to analyze (non)prioritized composite endpoints.

Statistics in medicine·2019
Same author

Recent Developments in the Prevention and Treatment of Missing Data.

Therapeutic innovation & regulatory science·2018
Same author

Statistical controversies in clinical research: futility analyses in oncology-lessons on potential pitfalls from a randomized controlled trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same journal

Optimal Weighted Tests for Replication Studies and the 'Two-Trials Rule' With Multiple Hypotheses.

Statistics in medicine·2026
Same journal

Identifiable Copula-Double-Cox Models: A Fully Parametric Framework for Dependent Right-Censored Survival Data.

Statistics in medicine·2026
Same journal

Moving From Individualized Risk-Based Prevention to Benefit-Based Prevention: Estimating Individualized Life-Years Gained From Prevention Services as a Basis for Eligibility.

Statistics in medicine·2026
Same journal

A Mixture of Distributed Lag Non-Linear Models to Account for Spatially Heterogeneous Exposure-Lag-Response Associations.

Statistics in medicine·2026
Same journal

Practical Considerations for Gaussian Process Modeling for Causal Inference in Quasi-Experimental Studies With Panel Data.

Statistics in medicine·2026
Same journal

Covariate Adjustment for Wilcoxon Two Sample Statistic and Test.

Statistics in medicine·2026
See all related articles

This study introduces novel likelihood methods for analyzing multivariate categorical data using global odds ratios. The approach offers a flexible framework for various study designs, enabling robust parameter estimation and hypothesis testing.

Area of Science:

  • Statistics
  • Biostatistics
  • Data Analysis

Background:

  • Multivariate categorical data analysis presents challenges in modeling complex associations.
  • Existing methods may lack flexibility for diverse study designs like longitudinal or repeated measures.
  • Efficient parameter estimation and hypothesis testing are crucial for drawing valid conclusions.

Purpose of the Study:

  • To present a flexible likelihood-based framework for analyzing multivariate categorical data.
  • To incorporate marginal mean functions and global odds ratios for association modeling.
  • To accommodate various complex study designs including repeated measurements and longitudinal studies.

Main Methods:

  • Utilizes likelihood methods to specify the joint distribution of multivariate categorical data.

Related Experiment Videos

  • Employs marginal mean functions and global odds ratios to model associations.
  • Develops simple algorithms for parameter estimation and hypothesis testing.
  • Main Results:

    • The proposed method allows flexible formulation for diverse study designs.
    • It enables robust parameter estimation and hypothesis testing for complex associations.
    • The approach is illustrated with a practical data example.

    Conclusions:

    • The developed likelihood methods provide a powerful and flexible tool for multivariate categorical data analysis.
    • Global odds ratios offer a comprehensive way to assess associations.
    • The method is applicable to a wide range of observational and experimental study designs.