Related Experiment Video
Updated: Jul 31, 2026

Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
Published on: September 11, 2018
[Pathomorphologic changes in the sympathetic portion of the autonomic nervous system and cardiovascular pathology]
1Cardiology Research Center, Moscow.
Abstract:
Neurohistochemical and ultrastructural study of the sympathetic innervation of the cardiovascular system indicated its important role in the age alterations and genesis of certain diseases. Early beginning (from the age of 30) of the involution of the heart adrenergic plexus is confirmed in healthy persons. Focal desympathization of the myocardium is detected in sudden cardiac death. A decrease of sympathetic plexus density in zones undergoing atherosclerotic changes is of importance in the genesis of atherosclerosis. In arterial hypertension a primary stage of sympathetic neurones hypertrophy is changed into the phase of the mediators exhaustion in the sympathetic plexus. Myocardiopathies are characterized by progressing myocardial desympathization. An important problem of cardiosurgery is methods of heart reinnervation at its transplantation.
More Related Videos
Related Concept Videos
The Sympathetic Nervous System
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
Sympathetic Signaling
Sympathetic preganglionic fibers release the neurotransmitter acetylcholine (ACh) onto the ganglionic neurons in the...
Sympathetic Activation
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's phenomenon, is a...
Heart Failure II: Pathophysiology

