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Related Experiment Videos

D-xylose testing.

R M Craig1, E D Ehrenpreis

  • 1Division of Gastroenterology/Hepatology, Northwestern University Medical School, Chicago, IL 60611, USA.

Journal of Clinical Gastroenterology
|September 9, 1999
PubMed
Summary
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D-xylose testing aids in diagnosing malabsorption and celiac disease. Recent advances enhance its use in evaluating diarrhea, particularly in acquired immunodeficiency syndrome, and understanding absorption mechanisms.

Area of Science:

  • Gastroenterology and clinical diagnostics.
  • Absorption physiology and disease pathology.

Background:

  • D-xylose testing is a historical tool for assessing small intestinal absorption.
  • Advances in serologic tests for celiac disease and understanding of malabsorption have evolved.
  • New diagnostic modalities like breath testing offer alternative methods for malabsorption evaluation.

Purpose of the Study:

  • To review the current literature on D-xylose testing.
  • To highlight advances in understanding D-xylose absorption.
  • To explore the role of D-xylose testing in modern diagnostic algorithms for malabsorption and diarrhea.

Main Methods:

  • Comprehensive literature review of D-xylose testing.
  • Analysis of D-xylose testing's relationship with other diagnostic methods.

Related Experiment Videos

  • Evaluation of D-xylose absorption in specific clinical contexts like celiac disease and acquired immunodeficiency syndrome.
  • Main Results:

    • D-xylose testing's relevance is re-evaluated in light of newer diagnostic tools.
    • Understanding of D-xylose absorption has advanced, differentiating between transcellular and paracellular transport.
    • D-xylose testing remains valuable in specific scenarios, especially when integrated into diagnostic algorithms.

    Conclusions:

    • D-xylose testing continues to be a useful tool for evaluating malabsorption and diarrhea.
    • Integration of D-xylose testing with newer methods like serologic tests and breath tests optimizes diagnostic accuracy.
    • Proposed algorithms can guide the effective use of D-xylose testing in clinical practice.